diff --git a/packages/discord.js/src/managers/ApplicationCommandManager.js b/packages/discord.js/src/managers/ApplicationCommandManager.js
index 8f6ce5310..6f23bbe2d 100644
--- a/packages/discord.js/src/managers/ApplicationCommandManager.js
+++ b/packages/discord.js/src/managers/ApplicationCommandManager.js
@@ -258,7 +258,6 @@ class ApplicationCommandManager extends CachedManager {
       type: command.type,
       options: command.options?.map(option => ApplicationCommand.transformOption(option)),
       default_member_permissions,
-      dm_permission: command.dmPermission ?? command.dm_permission,
       integration_types: command.integrationTypes ?? command.integration_types,
       contexts: command.contexts,
     };
diff --git a/packages/discord.js/src/structures/ApplicationCommand.js b/packages/discord.js/src/structures/ApplicationCommand.js
index 37eff9e46..eef940d57 100644
--- a/packages/discord.js/src/structures/ApplicationCommand.js
+++ b/packages/discord.js/src/structures/ApplicationCommand.js
@@ -140,18 +140,6 @@ class ApplicationCommand extends Base {
       this.defaultMemberPermissions ??= null;
     }
 
-    if ('dm_permission' in data) {
-      /**
-       * Whether the command can be used in DMs
-       * <info>This property is always `null` on guild commands</info>
-       * @type {?boolean}
-       * @deprecated Use {@link ApplicationCommand#contexts} instead.
-       */
-      this.dmPermission = data.dm_permission;
-    } else {
-      this.dmPermission ??= null;
-    }
-
     if ('integration_types' in data) {
       /**
        * Installation context(s) where the command is available
@@ -224,7 +212,6 @@ class ApplicationCommand extends Base {
    * @property {ApplicationCommandOptionData[]} [options] Options for the command
    * @property {?PermissionResolvable} [defaultMemberPermissions] The bitfield used to determine the default permissions
    * a member needs in order to run the command
-   * @property {boolean} [dmPermission] Whether the command is enabled in DMs
    */
 
   /**
@@ -341,15 +328,6 @@ class ApplicationCommand extends Base {
     return this.edit({ defaultMemberPermissions });
   }
 
-  /**
-   * Edits the DM permission of this ApplicationCommand
-   * @param {boolean} [dmPermission=true] Whether the command can be used in DMs
-   * @returns {Promise<ApplicationCommand>}
-   */
-  setDMPermission(dmPermission = true) {
-    return this.edit({ dmPermission });
-  }
-
   /**
    * Edits the options of this ApplicationCommand
    * @param {ApplicationCommandOptionData[]} options The options to set for this command
@@ -386,7 +364,6 @@ class ApplicationCommand extends Base {
     if (command.id && this.id !== command.id) return false;
 
     let defaultMemberPermissions = null;
-    let dmPermission = command.dmPermission ?? command.dm_permission;
 
     if ('default_member_permissions' in command) {
       defaultMemberPermissions = command.default_member_permissions
@@ -412,7 +389,6 @@ class ApplicationCommand extends Base {
       // TODO: remove ?? 0 on each when nullable
       (command.options?.length ?? 0) !== (this.options?.length ?? 0) ||
       defaultMemberPermissions !== (this.defaultMemberPermissions?.bitfield ?? null) ||
-      (dmPermission !== undefined && dmPermission !== this.dmPermission) ||
       !isEqual(command.nameLocalizations ?? command.name_localizations ?? {}, this.nameLocalizations ?? {}) ||
       !isEqual(
         command.descriptionLocalizations ?? command.description_localizations ?? {},
diff --git a/packages/discord.js/src/structures/Message.js b/packages/discord.js/src/structures/Message.js
index 8bf1222c1..f052113e2 100644
--- a/packages/discord.js/src/structures/Message.js
+++ b/packages/discord.js/src/structures/Message.js
@@ -413,33 +413,6 @@ class Message extends Base {
       this.interactionMetadata ??= null;
     }
 
-    /**
-     * Partial data of the interaction that a message is a reply to
-     * @typedef {Object} MessageInteraction
-     * @property {Snowflake} id The interaction's id
-     * @property {InteractionType} type The type of the interaction
-     * @property {string} commandName The name of the interaction's application command,
-     * as well as the subcommand and subcommand group, where applicable
-     * @property {User} user The user that invoked the interaction
-     * @deprecated Use {@link Message#interactionMetadata} instead.
-     */
-
-    if (data.interaction) {
-      /**
-       * Partial data of the interaction that this message is a reply to
-       * @type {?MessageInteraction}
-       * @deprecated Use {@link Message#interactionMetadata} instead.
-       */
-      this.interaction = {
-        id: data.interaction.id,
-        type: data.interaction.type,
-        commandName: data.interaction.name,
-        user: this.client.users._add(data.interaction.user),
-      };
-    } else {
-      this.interaction ??= null;
-    }
-
     if (data.poll) {
       /**
        * The poll that was sent with the message
diff --git a/packages/discord.js/typings/index.d.ts b/packages/discord.js/typings/index.d.ts
index ac7242ab0..36aba253d 100644
--- a/packages/discord.js/typings/index.d.ts
+++ b/packages/discord.js/typings/index.d.ts
@@ -429,8 +429,6 @@ export class ApplicationCommand<PermissionsFetchType = {}> extends Base {
   public description: string;
   public descriptionLocalizations: LocalizationMap | null;
   public descriptionLocalized: string | null;
-  /** @deprecated Use {@link ApplicationCommand.contexts} instead */
-  public dmPermission: boolean | null;
   public guild: Guild | null;
   public guildId: Snowflake | null;
   public get manager(): ApplicationCommandManager;
@@ -460,7 +458,6 @@ export class ApplicationCommand<PermissionsFetchType = {}> extends Base {
   public setDefaultMemberPermissions(
     defaultMemberPermissions: PermissionResolvable | null,
   ): Promise<ApplicationCommand<PermissionsFetchType>>;
-  public setDMPermission(dmPermission?: boolean): Promise<ApplicationCommand<PermissionsFetchType>>;
   public setOptions(
     options: readonly ApplicationCommandOptionData[],
   ): Promise<ApplicationCommand<PermissionsFetchType>>;
@@ -2207,8 +2204,6 @@ export class Message<InGuild extends boolean = boolean> extends Base {
   public get guild(): If<InGuild, Guild>;
   public get hasThread(): boolean;
   public id: Snowflake;
-  /** @deprecated Use {@link Message.interactionMetadata} instead. */
-  public interaction: MessageInteraction | null;
   public interactionMetadata: MessageInteractionMetadata | null;
   public get member(): GuildMember | null;
   public mentions: MessageMentions<InGuild>;
@@ -4694,7 +4689,6 @@ export type AllowedThreadTypeForTextChannel = ChannelType.PublicThread | Channel
 export interface BaseApplicationCommandData {
   name: string;
   nameLocalizations?: LocalizationMap;
-  dmPermission?: boolean;
   defaultMemberPermissions?: PermissionResolvable | null;
   nsfw?: boolean;
   contexts?: readonly InteractionContextType[];
@@ -6338,14 +6332,6 @@ export interface MessageInteractionMetadata {
   triggeringInteractionMetadata: MessageInteractionMetadata | null;
 }
 
-/** @deprecated Use {@link MessageInteractionMetadata} instead. */
-export interface MessageInteraction {
-  id: Snowflake;
-  type: InteractionType;
-  commandName: string;
-  user: User;
-}
-
 export interface MessageMentionsHasOptions {
   ignoreDirect?: boolean;
   ignoreRoles?: boolean;
diff --git a/packages/discord.js/typings/index.test-d.ts b/packages/discord.js/typings/index.test-d.ts
index 036d7250d..266205746 100644
--- a/packages/discord.js/typings/index.test-d.ts
+++ b/packages/discord.js/typings/index.test-d.ts
@@ -705,7 +705,6 @@ client.on('clientReady', async client => {
   await client.application?.commands.edit(globalCommandId, { defaultMemberPermissions: null });
   await globalCommand?.edit({ defaultMemberPermissions: null });
   await globalCommand?.setDefaultMemberPermissions(null);
-  await guildCommandFromGlobal?.edit({ dmPermission: false });
 
   // @ts-expect-error
   await client.guilds.cache.get(testGuildId)?.commands.fetch(guildCommandId, { guildId: testGuildId });